在第4外显子下游插入了loxP-引导的诺姆西林筛选 cassette,而在第3外显子上游则插入了loxP位点。短暂的Cre表达去除掉了筛选 cassette,留下3和4号外显子周围的loxP位点。通过Southern blotting和PCR,确认了基因型的精确定位(来源:J:106419, J:136334)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部