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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(Ins2-E3*734)3Dvs
Alias:
Tg(RIP-E3-734)3Dvs
RIP-DL734
DL734
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基础信息
表型特征
文献报道
将大鼠胰岛素基因的启动子插入到腺病毒早期区3(E3)序列的上游,其中11.6K开放阅读框的两个甲硫氨酸被替换为密码子,然后这个构建被注入到NOD/LtDvs的卵母细胞中(J:106340)。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
3618341
Not Applicable
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1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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