将大鼠胰岛素基因的启动子插入到腺病毒早期区3(E3)序列的上游,其中11.6K开放阅读框的两个甲硫氨酸被替换为密码子,然后这个构建被注入到NOD/LtDvs的卵母细胞中(J:106340)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Applicable
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显性
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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