bm13突变包括四个核苷酸变异,导致第114位(亮氨酸替换为甘氨酸)、116位(苯丙氨酸替换为酪氨酸)和119位(谷氨酸替换为天冬氨酸)的氨基酸变化,第118位位点是无义突变。这种突变据信是通过基因转换,H-2Kb作为供体位点发生的。(来源:J:106337)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6ByKh x BALB/cByKh)F1
Spontaneous
核苷酸替换
--
1
12
15

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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