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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Chm
tm1Seab
Alias:
Chm
3lox
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基础信息
表型特征
文献报道
设计了一种靶向载体,其在exon 4周围插入了loxP位点。在内含子4中插入了含额外loxP位点的诺卡因和斯皮替诺霉素基因座。删除exon 4会导致框架突变,产生一个早终止密码子。(来源:J:105458)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3617902
129X1/SvJ
Targeted
插入
--
1
4
4
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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