设计了一种靶向载体,通过替换单位是诺卡因抗性基因座,目标去除12和13号外显子,包括包含在最后一个保守的SNF2/SWI2家族保守区域的28个高度保守的氨基酸。Northern blot实验确认了突变小鼠中转录的缺失。(来源:J:105544)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入,基因内删除
--
1
2
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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