在启动子序列、外显子1和2的周围插入了LoxP位点。通过FLP介导的重组,去除了带有frt标记的新基因座。删除这段序列会移除起始密码子、5'的SNAG抑制域以及蛋白质的前三个锌指DNA结合区域。(来源:J:105294)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
插入
--
1
--
19

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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