Dclk1^tm1.1Jgg

Cre mediated recombination was used to remove exon 3. Removal of this exon is predicted to result in splicing of exon 2 to a downstream exon, resulting in out-of-frame splicing. Exon 3 encodes the majority of the R1 repeat. Mutants demonstrated abolishment of isoforms containing the DCX domain. (J:105300)