Kpnb1^{Gt(pU-hachi)1Arak}

The pU-hachi gene trap vector, containing an IRES-betageo, was inserted into the promoter region of the locus in reverse orientation of transcription. This vector was designed to be exchangeable upon cre expression. Expression of the endogenous locus was decreased by about 60-80% of wild-type, demonstrating this allele is a hypomorph. (J:105350)