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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Del(2Hoxdi)25Ddu
Alias:
Del25Ddu
Del(i)
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基础信息
表型特征
文献报道
在Tg(Sycp1-cre)4Min背景下,通过特异性有丝分裂重组,在Hoxdtm15Ddu和Hoxdtm16Ddu杂交中产生。这个过程导致Hoxd4至Hoxd8区域的大部分DNA从Hox基因簇中删除。(来源:J:105255)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
3616700
129S2/SvPas
Targeted
基因间区删除
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3
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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