在Evx2/Hoxd13tm3.1Ddu和Hoxdtm15Ddu杂交,同时在Tg(Sycp1-cre)4Min存在下,通过有目标的减数分裂重组产生。Hoxd8、Hoxd9、Hoxd10、Hoxd11、Hoxd12和Hoxd13在Hoxd基因簇中都被删除。大部分Hoxd4和Hoxd8之间的'i'区域得以保留。(来源:J:103924)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S2/SvPas
Targeted
Intergenic deletion, Intragenic deletion
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12

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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