一个3kb的MC1-neomycin抗性 cassette替换了所有三个外显子。 Western blot分析并未在纯合突变小鼠的脾液中检测到蛋白质。(来源:J:57995)
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A 3kb MC1-neomycin resistance cassette replaced all three exons. Western blot analysis did not detect protein in spleen lysates from homozygous mutant mice. (J:57995)