这个基因组区域,包含分泌信号和部分Ig域,被替换了lacZ和neo的插入片段。lacZ的表达在副鼻腔腺、前背侧丘脑核、下丘脑、大脑皮层的第五层以及小脑中被检测到。然而, Western blot在突变大脑中没有检测到蛋白质。(来源:J:61081, J:104862)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129X1/SvJ
Targeted
插入,基因内删除
--
1
--
10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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