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中文
一个诺他霉素抗性基因座替换了大约2.5kb的序列，包括第二和第三外显子，它们编码CUB域的N端部分。这个缺失导致了移框，使得在原始框架中信号肽之后没有下游序列，而在新框架中只有21个氨基酸序列被翻译。逆转录PCR在突变体中未能检测到野生型转录本。在突变的MEFs中未检测到蛋白质。(来源：J:104148)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
