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中文
设计了一个靶向载体，其中4-6号外显子通过loxP位点进行了敲除。这个区域编码了双甘氨酸重复域。去除这些外显子预计会导致产生一个无法抑制Nfe2l2活性的片段性缺失版本。这种等位基因的蛋白表达量降低，表现为部分功能减弱。(来源：J:103791, J:146190)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
