将一个包含splice接受器、IRES-EGFP-cre、pA序列和kanamycin/neomycin抗性基因的磁带插入到了特定位置。预期Cre表达会在前体和成体的间充质中发生。在E9.5-11.5期的突变胚胎中未检测到EGFP活性,可能是因为IRES序列介导的EGFP0cre融合蛋白表达水平较低。(来源:J:102739)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
2
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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