将一个包含splice接受器、IRES-EGFP-cre、pA序列和kanamycin/neomycin抗性基因的磁带插入到了特定位置。预期Cre表达会在前体和成体的间充质中发生。在E9.5-11.5期的突变胚胎中未检测到EGFP活性,可能是因为IRES序列介导的EGFP0cre融合蛋白表达水平较低。(来源:J:102739)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count