设计了一个靶向载体,用于替换3的部分,包括从GTP结合域内P-loop模式6个bp下游起始的第二个ATG。 Western blot在突变大脑中未能检测到蛋白质。(来源:J:103760)
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A targeting vector was designed to replace part of 3, including the second ATG which starts from 6 bp downstream of the P-loop motif within the GTP-binding domain. Western blot failed to detect protein in mutant brain. (J:103760)