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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Gnas
tm5.1Lsw
Alias:
Galphas
fl
Gnas
lox
E1
fl
Gsalpha
fl
Gsalpha
f
Gnas
fl
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基础信息
表型特征
文献报道
设计了一个靶向载体,包含一个在exon 1上游-1601位置的floxed neo以及exon 1后方419位置的第三个loxP座。与小鼠中携带cre的生殖细胞杂交后,neo被剔除,exon 1被loxP座包裹。(来源:J:99237)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3609165
129S6/SvEvTac
Targeted
插入
--
1
18
58
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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