设计了一个靶向元件,通过Cre介导的重组去除3-6号外显子,导致7号外显子产生插入突变,产生一个早发终止密码子。这个等位基因是通过Men1tm2.1Mmey生成的(来源:J:88588)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
基因内删除
--
1
23
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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