这个转基因过表达的是大鼠Agt基因,受Adipocyte-specific Fabp4启动子的控制。Northern blot和RT-PCR结果显示,Agt在脂肪组织中特异性表达,肌肉和心脏中检测到少量mRNA,而肝脏和肾脏中则没有。多条克隆线产生了,其中Line 2表现出Agt表达的最高水平。(来源:J:73163)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA/2)
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插入
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1
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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