将细菌的lacZ基因插入,使其由内源性基因驱动表达β-半乳糖苷酶。在所有分析的组织中都检测到了RNA转录,且这个等位基因在所有检查的器官中也都能检测到β-半乳糖苷酶的表达,但在许多器官中,染色仅限于血管。 (Translation from: A bacterial lacZ gene was inserted into the genome, such that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts are detectable in all tissues examined, and beta-galactosidase expression from this allele is also detectable in all organs examined, with staining restricted to blood vessels in many.) (Source: No specific reference provided)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count