将细菌的lacZ基因插入,通过原生基因启动子驱动β-半乳糖苷酶的表达。RT-PCR检测结果显示所有检查的组织中都存在基因转录;β-半乳糖苷酶的表达在大脑、脊髓、眼睛、肝脏、胰腺、肾脏、输尿管、甲状旁腺、气管、垂体、肾上腺、骨骼肌、皮肤、睾丸、前列腺和子宫都可检测到。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
载体插入引起的破坏
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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