Mapkapk2^tm1Dgen

将细菌的lacZ基因插入，使其由内源性基因驱动β-半乳糖苷酶的表达。RT-PCR分析在所有检查的组织中都检测到了基因转录，除了大脑皮层、胰腺、骨髓和子宫；所有组织中都可检测到β-半乳糖苷酶的表达。 (Translation from: A bacterial lacZ gene was inserted into the genome, with the endogenous promoter driving expression of beta-galactosidase. RT-PCR analysis revealed gene transcript presence in all tissues except the cortex, pancreas, bone marrow, and uterus; beta-galactosidase expression was detectable in every tissue examined.)