将细菌的lacZ基因插入,使其由内源性基因启动子驱动β-半乳糖苷酶的表达。在肝脏、肾脏、脾脏、胸腺、骨髓、皮肤、胆囊、肾上腺、唾液腺、胃、小肠、大肠、卵巢和子宫中可检测到RNA转录本。然而,这个等位基因的β-半乳糖苷酶表达在大脑、脊髓、眼睛、胸腺、脾脏、骨髓、心脏、肺、肝脏、胰腺、肾脏、膀胱、甲状腺、气管、垂体、肾上腺、骨骼肌、皮肤、卵巢、子宫和子宫颈中也可见。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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