将细菌的lacZ基因插入,使其由内源性基因启动子驱动β-半乳糖苷酶的表达。RT-PCR分析显示,在所有检测的组织中都检测到了基因转录,其中在大脑皮层、脑干、肾上腺和睾丸的水平最高。而这个等位基因的β-半乳糖苷酶表达则在所有检查的器官中均可检测到。([来源])

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
2
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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