将细菌的lacZ基因插入,使得内源性基因驱动β-半乳糖苷酶的表达。RT-PCR分析在所有测试组织中都检测到了基因转录,但这种等位基因在整体大脑基底节区域显示出强烈的β-半乳糖苷酶表达,而在大脑冠状切片上未检测到表达。在卵巢的间质中观察到适度的染色。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部