将细菌的lacZ基因插入,使其由内源性基因驱动表达β-半乳糖苷酶。在大脑、皮层、基底核、小脑、脑干、嗅球、脊髓、眼、心脏、肺、脾、淋巴结、皮肤、膀胱、垂体、肾上腺、骨骼肌、舌、胃、小肠、大肠、盲肠、睾丸、附睾、凝血腺、前列腺、卵巢、子宫和白色脂肪中可检测到RNA转录本。lacZ(β-半乳糖苷酶)的表达在大脑和睾丸中可被检测到。 (Source: The original text)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
--
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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