Ackr4^tm1Dgen

将细菌的lacZ基因插入，使其由内源性基因驱动β-半乳糖苷酶的表达。RT-PCR分析显示所有测试组织中都存在基因转录，而这个等位基因在大脑、脊髓、心脏、胰腺、气管、喉、食管、舌头、皮肤和男性生殖系统中能检测到β-半乳糖苷酶的表达。 (Source: The inserted bacterial lacZ gene is expressed under the endogenous promoter, with detectable beta-galactosidase activity observed in brain, spinal cord, heart, pancreas, trachea, larynx, esophagus, tongue, skin, and male reproductive tissues through RT-PCR analysis.)