将细菌的lacZ基因插入,使其由内源性基因驱动β-半乳糖苷酶的表达。在所有分析的组织中都能检测到RNA转录本。在大脑、硬腭腺、主动脉、心脏、肺、肾、输尿管、唾液腺、舌、外耳、男性和女性生殖系统中,都能检测到lacZ(β-半乳糖苷酶)的表达。在许多可检测到表达的组织中,血管中也发现了lacZ表达。(Source: The original text)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
1
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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