A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a gene transcript in brain, spinal cord, eye, heart, kidney, pituitary gland, adrenal gland, stomach, large intestine, seminal vesicle, coagulating gland, ovary and uterus; beta-galactosidase expression is detectable in brain, spinal cord, eye, spleen, lymph nodes, esophagus, parathyroid gland, pituitary gland, salivary glands, tongue, male and female reproductive systems.