将细菌的lacZ基因插入,使其由内源性基因启动子驱动β-半乳糖苷酶的表达。RT-PCR分析在所有检查的组织中都检测到了基因转录;除淋巴结和骨髓外,大多数组织中都能检测到β-半乳糖苷酶的表达。 (Source: The lacZ gene from a bacterial strain was inserted, with its endogenous promoter driving expression of beta-galactosidase. RT-PCR revealed gene transcript presence in all tissues examined, except for lymph nodes and bone marrow, where beta-galactosidase expression was detectable.)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count