将细菌的lacZ基因插入,使其由内源性基因驱动β-半乳糖苷酶的表达。RT-PCR检测结果显示在大脑、脊髓、脾、胸腺、淋巴结和膀胱中存在基因转录;在大脑和睾丸中能检测到β-半乳糖苷酶表达,但在脊髓、脾、胸腺、淋巴结和膀胱中未见。 (Translation from: A bacterial lacZ gene was inserted into the genome, with the endogenous promoter driving expression of beta-galactosidase. RT-PCR analysis revealed gene transcripts in brain, spinal cord, spleen, thymus, lymph nodes, and urinary bladder; beta-galactosidase expression was detected in brain and testis, but not in the spinal cord, spleen, thymus, lymph nodes, or urinary bladder, as per the source.)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count