Pde1b^tm1Dgen

将细菌的lacZ基因插入，使其由内源性基因驱动β-半乳糖苷酶的表达。RT-PCR分析显示，除了胰腺外，大多数检测的组织中都存在基因转录；β-半乳糖苷酶在大脑、眼睛、外耳和男性生殖系统中可检测到表达。 (Source: The inserted bacterial lacZ gene is expressed under the endogenous promoter, with detectable beta-galactosidase expression in brain, eyes, external ear, and male reproductive system by RT-PCR analysis, except for the pancreas.)