A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RT-PCR analysis detects a gene transcript in all tissues analyzed, beta-galactosidase expression from this allele is detectable in brain, spleen, liver, kidney, trachea, larynx, thyroid gland, pituitary gland, adrenal glands, skin, male and female reproductive systems.