Lhx8^tm1Vpa

Exons 3-5 were replaced with a lacZ reporter. The deleted region encodes the two LIM domains and part of the homeodomain. Expression of the mutant allele was shown in the maxillary and mandibular processes of the first branchial arch, the pinna, and the medial ganglionic eminence of the telencephalon, corresponding to expression of the endogenous locus. (J:101205)