在第6外显子插入了一个IRES-lacZ-puro,这导致删除了编码303-364氨基酸的第7外显子。原位杂交显示lacZ在胚胎全身范围内广泛表达,特别是在鳃弓、假定的手和体节中。北印迹显示在不同胚胎阶段都有表达。(来源:J:101173)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入,基因内删除
--
1
2
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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