将Neurod1tm1Kan基因与小鼠中在生殖细胞中表达Cre的结果导致了floxed neo标记的丢失,但loxP序列仍存在于整个编码序列的首尾。对小鼠脑蛋白提取物的 Western blot 检测显示突变蛋白水平与野生型相当。(来源:J:101098)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count