将Gad1tm1Tama小鼠与体内含有Cre重组酶的雌雄配子相结合,移除了含loxP标记的新突变neo。 Western blot结果显示,这些转基因小鼠大脑皮层中GFP的含量高于neo存在时的对照组。荧光显微镜检查也证实了在突变大脑样本中观察到的相同结果。(来源:J:86389)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6NCrlj x CBA/JNCrlj)F1
Targeted
插入
--
1
3
262

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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