将Gad1tm1Tama小鼠与体内含有Cre重组酶的雌雄配子相结合,移除了含loxP标记的新突变neo。 Western blot结果显示,这些转基因小鼠大脑皮层中GFP的含量高于neo存在时的对照组。荧光显微镜检查也证实了在突变大脑样本中观察到的相同结果。(来源:J:86389)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count