一种基因陷阱载体pGTO,包含一个splice接受器Betageo和SV40的pA序列,被插入到该基因座位的第4个内含子中。逆转录PCR在所有测试的组织中都没有检测到转录本。Northern blot和Western blot分别证实了突变大脑样本中所有形式的转录本和蛋白质均缺失。(来源:J:100826)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
基因捕获载体的插入
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1
3
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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