Exon 1,包含ATG起始密码子的部分以及内含子1,被诺卡因抗性基因座替换。 Western blot对突变肝提取物的检测确认了没有蛋白质存在。(来源:J:100280)
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Exon 1, containing the ATG, and part of intron 1 were replaced by neomycin resistance cassette. Western blot of mutant liver lysates confirmed absence of protein. (J:100280)