将Atg7tm1Tchi基因与小鼠中在卵母细胞表达Cre重组酶交叉会导致exon 14的丢失。突变体中未检测到转录本或蛋白质。通过检测新生儿肝脏中的ATG连接系统,也发现了活性丧失(来源:J:100199)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6NCrlj x CBA/JNCrlj)F1
Targeted
基因内删除
--
1
2
36

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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