一个neo/ura3 cassette替换了前三个外显子。通过小肠的免疫印迹实验,确认了突变体中没有蛋白质表达。对突变肠段使用针对TH1区域的抗体进行免疫染色,结果显示了预期的无信号,来源是(J:100193)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/SvImJ
Targeted
插入,基因内删除
--
1
2
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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