将cre重组酶基因插入到第一个编码外显子,接着是frt标记的诺卡因 cassette,然后是帧移突变插入到exon 5。这个等位基因在发育过程中特异性表达cre重组酶,是在使用了与Cd19tm1(cre)Cgn相同的构建,只是使用了CCB ES细胞进行靶向的。(来源:J:27463)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S/SvEv-Gpi1c
Targeted
插入
--
1
3
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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