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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Rr27
tm3Tilg
Alias:
H19
Ku site-
H19
tm5Tilg
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基础信息
表型特征
文献报道
在 imprinting 控制区的超敏感位点 1 和 2 的 DNA 结合位点引入了改变 ATCGAT 为 CACGCA 的突变。在睾丸中表达 cre 融合酶后,一个 loxP 突变的 neomycin 抗性基因被剔除了。(来源:J:98880)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
3580481
129S7/SvEvBrd-Hprt1b-m2
Targeted
插入
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1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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