在exon 2编码的必需RGS区域,序列被myc标记的Axin2 cDNA替换。 Western blot检测到突变等位基因中的myc表达,但未检测到内源性蛋白。(来源:J:98893)
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The sequence in exon 2 encoding the essential RGS domain was replaced by myc-tagged Axin2 cDNA. Western blot detected myc expression in the mutant allele and failed to detect endogenous protein. (J:98893)