这种突变通过与Jackson实验室的recoil wobbler 2的补救测试被证明是rcw的等位基因。检测到一个c.1010G>A的转换,导致G变成E(p.G337E)的氨基酸替换。这与Grm1rcw-4J中的变异相同,推测可能源自单一的突变事件。(来源:J:127311)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Spontaneous
单点
隐性
1
4
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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