大部分外显子,包括sema域的编码区域,在插入loxP-IRES Tak PGK-neo cassette后被删除。 Western blot结果显示这些突变体具有野生型的缺失等位基因。(来源:J:98330)
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Most of the exon, including the coding region for the sema domain, was deleted upon the insertion of a loxP-IRES Tak PGK-neo cassette. Western blot confirmed that mutants have the null allele. (J:98330)