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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Mfge8
Gt(KST227)Byg
Alias:
Mfge8
Gt1(pGT1-pfs)Des
Mfge8
Gt(Betageo)1Zm
Mfge8
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基础信息
表型特征
文献报道
一种基因陷阱载体pGT1TMpfs被插入到C1域下游7号内含子的位点,它包含了β-半乳糖苷酶和抗氨苄青霉素基因。事件产生的转录本编码了一个融合蛋白,由该位点的N端序列至C1域,随后是TM域和β-geo基因陷阱序列。(来源:J:98314)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3578644
129P2/OlaHsd
Gene trapped
基因捕获载体的插入
--
1
--
26
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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