This transgene contains Cre recombinase and human placental alkaline phosphatase under the control of Gdf5 promoter and enhancer elements. A BAC containing the Gdf5 locus was modified by the insertion of a cre-IRES-ALPP into the translational start site to create the transgene. Gdf5 drives expression in developing joints. This line represents three that were created. (J:97780)