Tgiftm1Caw小鼠与在生殖细胞中表达Cre的 mice杂交,产生了这个突变体,其中删除了exons 2和3, Western blot结果显示突变胚胎中没有蛋白质表达。(来源:J:97642)
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Tgiftm1Caw mice were crossed with mice expressing cre in the germline to produce this allele in which exons 2 and 3 are deleted. Western blot demonstrated lack of protein in mutant embryos. (J:97642)