(6-11号外显子,包含了基因的80%,被替换了为neo。对淋巴组织的 Western blot 检测显示突变体中没有野生型蛋白存在。(来源:J:96535))
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Exons 6-11, encompassing 80% of the gene, were replaced with a neo. Western blot of lymphoid tissues demonstrated the lack of wild-type protein in mutants. (J:96535)